Getting Personal: Omics Of The Heart

Jane Ferguson:                 Hi, everyone. Welcome to Getting Personal: Omics of the Heart. This is podcast episode 16 from May 2018. I'm Jane Ferguson from Vanderbilt University Medical Center and this podcast is brought to you by Circulation Genomic and Precision Medicine and the AHA Council on Genomic and Precision Medicine. Jane Ferguson:                 This month we talked to Dr. Caitrin McDonough from the University of Florida. We briefly mentioned her paper in last month's episode Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study, but we wanted to go into it in more depth this month. Caitrin shared with us that this manuscript actually resulted from student course work and was a collaborative effort between students and instructors. The manuscript highlights has successful as approach can be both in increasing student engagement and as an effective way to do high quality research. You can hear her talk more about her innovative approach to student learni

Jane Ferguson:                 Hello, welcome to Getting Personal: Omics of the Heart. This is podcast Episode 15 from April 2018. I'm Jane Ferguson, an Assistant Professor of Medicine at Vanderbilt University Medical Center, and this podcast is brought to you by Circulation Genomic and Precision Medicine and the AHA Council on Genomic and Precision Medicine.                                                 As usual, we have a great lineup of papers in Circ Genomic and Precision Medicine this month. The first is actually the subject of our interview this month. Sony Tuteja talked to Craig Lee from the University of North Carolina about his manuscript entitled, "Clinical Outcomes and Sustainability of Using CYP2C19 Genotype Guided Antiplatelet Therapy After Percutaneous Coronary Intervention." This manuscript investigated the use of pharmacogenomics to improve treatment after PCI, and you can hear a lot more about it directly from the first author later in the podcast.                                         

Jane Ferguson:                 Hello, welcome to Getting Personal: Omics of the Heart, episode 14 from March, 2018. I'm Jane Ferguson, and this podcast is brought to you by Circulation Genomic and Precision Medicine, and the AHA Council on Genomic and Precision Medicine. This month I talk to Deirdre Tobias about her research on branch gene amino acids and incident cardiovascular disease in women, and I got the chance to talk to Kiran Musunuru, the new editor in chief of Circulation Genomic and Precision Medicine, about his take of the publishing process and new directions the journal has been taking.                                                 I'm joined today by Dr. Deirdre Tobias who is an instructor in medicine at the Brigham and Women's Hospital in Boston. Dr. Tobias is the first author of a paper entitled Circulating Branch Chain Amino Acids and CBD Risk in Women that is published this month in Circulation Genomic and Precision Medicine. Deirdre is also presenting this work at the lifestyle sessions

Transcript of the February Podcast, “Getting Personal: Omics of the Heart”, Episode 13   Hosted by Jane Ferguson   Assistant Professor at Vanderbilt University Medical Center & Associate Editor of the Circulation: Precision and Genomic Medicine journal of the American Heart Association Jane Ferguson:             Hello. This is episode 13 of Getting Personal: Omics of the Heart. It's February 2018. I'm Jane Ferguson, an assistant professor at Vanderbilt University Medical Center, an associate editor at Circulation: Precision and Genomic Medicine, and an occasional podcast host. This month, I talked to Kiran Musunuru and Svati Shah about how they spearheaded name changes for Circulation Cardiovascular Genetics and for the AHA Council on Functional Genomics and Translational Biology, and Andrew Landstrom talked to Kaytlyn Gerbin and Brock Roberts from the Allen Institute about some extremely cool work they are doing with CRISPR and IPS cells to create fluorescently tagged maps of live cells, which allowed th

Transcript for January 2018 Podcast Circulation: Genomic and Precision Medicine     Jane Ferguson:                 Hi, everyone. Happy New Year. You are listening to "Getting Personable: Omics of the Heart". I'm Jane Ferguson and this is episode twelve from January 2018.                                                  This month I have some exciting announcements to make. The journal formerly known as "Circulation: Cardiovascular Genetics" has a new name. As of this month, the podcast is brought to you by "Circulation: Genomic and Precision Medicine". We're still publishing papers focused on cardiovascular genetics but as genomics and other omics have expanded our scope has grown to so much more than just genetics.                                                 The new name, "Genomic and Precision Medicine" signifies the journals focus not only on genetics, but also genomics and all the other omic technologies and the feel of precision medicine. Along with the new name we have a new editing team. Dr. Kir

Jane Ferguson:                 Hi everyone. Welcome to Getting Personal: Omics of the Heart. This is episode 11 from December 2017. I'm Jane Ferguson, and this podcast comes to you courtesy of Circulation: Cardiovascular Genetics and the AHA Functional Genomics and Translational Biology Council. I'm particularity excited about our interview this month. Doctor Kent Arell from the Mayo Clinic talked to Doctor Jennifer Hall from the University of Minnesota about her role as Chief of the AHA institute for Precision Cardiovascular Medicine. This is a really exciting initiative, which is bringing together researchers, patients and stakeholder to foster the growth and development of cardiovascular genomic and precision medicine. Through their Precision Medicine Platform you can access a virtual big data research hub and find data, tools, and collaborations. The institute also provides funding for projects related to precision cardiovascular medicine. You can find out more and register to access the platform at preci

Jane Ferguson:                Hello, I'm Jane Ferguson and you are listening to Getting Personal: Omics of the Heart, the podcast from Circulation: Cardiovascular genetics, and the functional genomics and translational biology council of the AHA. This is episode ten, from November 2017.                                            November is always a big month for AHA and the annual Scientific Sessions were held in Anaheim, California, November 11th through 15th. For those of you who were able to attend, hopefully you came away feeling refreshed and invigorated and with your desired level of Disney merchandise. For those of you who could not attend, or who didn't make it to all of the genomic sessions, this month's episode should catch you up.                                            For the past several years, the FGTB Council has been organizing boot camps at AHA sessions to give people a chance for hands on learning in a flipped classroom model. This year was no exception and in addition to a clinical g

Jane Ferguson:                  Hi Everyone. Welcome to Getting Personal: Omics of the Heart, your podcast from Circulation Cardiovascular Genetics. I'm Jane Ferguson, an assistant professor at Vanderbilt University Medical Center and an associate editor at Circ Genetics. This is Episode 9 of the podcast from October 2017.                                                 This month we were on the road and traveled to sunny Orlando, Florida for the annual Scientific Sessions of the American Society of Human Genetics. While there, I had the chance to talk to some of the researchers presenting posters in the sessions on cardiovascular genetics and genomics, which you'll hear in just a moment. While at ASHG, we had the chance to organize a CRISPR-Cas9 genome editing boot camp. Those of you who attend a JR ATVB/PVD Scientific Sessions might have had the chance to participate in a boot camp in previous years, and this is the first time we were able to offer a boot camp at ASHG. These boot camps are based on a flipp

Jane Ferguson:                Hi, everyone. Welcome to Episode 08 of Getting Personal: -Omics of the Heart. I'm Jane Ferguson, and this podcast is brought Circulation Cardiovascular Genetics and the AJ Functional Genomics and Translational Biology Council. This is the September 2017 episode, and this month we delve into some of the newest research coming out in the October 2017 issue of CircGenetics. If you go on to the CircGenetics website at circgenetics.ahajournals.org, you can see the table of contents for the latest issue, and see sneak previews of upcoming papers that are published online in advance of the next issue. You can also more in-depth materials for each paper, like editorials and other resources, so it's a really nice way to keep up with the newest cardiovascular genomics research.                                            One particularly interesting paper included in the October 2017 issue is entitled "Diminished PRRX1 Expression Is Associated With Increased Risk of Atrial Fibrillation and

Speaker 1:                        Hi everyone. As a quick introduction, this is the full length recording of Anwar Chahal's interview with Calum MacRae from August 2017. A portion of this interview was included in episode seven of the Circulation Cardiovascular Genetics podcast "Getting Personal: Omics of the Heart". As we couldn't fit everything into that regular podcast episode, we've released the unedited version as a special, feature-length podcast. Enjoy. Dr Anwar Chahal:            My name is Dr. Anwar Chahal. I'm a Cardiology Fellow in Training from London, U.K., and I'm doing my research fellowship here at the Mayo Clinic, and I'm very honored and delighted to have our guest, Dr. Calum MacRae. I searched for Dr. Calum MacRae's biography online and it came up with a Wikipedia page talking about somebody who's a rugby coach. So, Dr. MacRae, I hope that's not another one of strings to your bow, that's something else that you manage to squeeze in amongst everything else that you do in your busy and punish

Jane Ferguson:                Hi everyone. Welcome to episode seven of Getting Personal, -Omics of the Heart. I'm Jane Ferguson, an assistant professor of medicine at Vanderbilt University Medical Center and the chair of the Publications and Professional Education Committee of the Functional Genomics and Translational Biology Council of the American Heart Association.                                            This month I'm particularly excited to announce a new venture. We have teamed up with the journal, Circulation: Cardiovascular Genetics to bring you this and future podcasts. CircGen publishes a lot of the most compelling research in cardiovascular genetics and genomics and precision medicine in cardiometabolic disease. We've already featured a lot of the research in previous episodes of the podcast. With this new collaboration, you can look forward to even more in-depth features of the newest research published in Circulation: Cardiovascular Genetics.                                            This m

Jane Ferguson:                Hi, everyone. Welcome to episode six of our podcast. I'm Jane Ferguson, the current chair of the Professional Education and Publications Committee of the Functional Genomics and Translational Biology Council of the American Heart Association. It's July as we're recording this, so hopefully all you listeners in the Northern Hemisphere are enjoying the summer and taking a break to catch up on your podcast queue, maybe while relaxing at the beach or while navigating the twists and turns of the airport security line.                                            In honor of summer, we're doing something a little different this month and featuring a bite-sized podcast with some research about how your vacation plans might be affecting your heart disease risk. For all our friends in the Southern Hemisphere, I'm sorry that this may be less relevant to you right now, but hopefully you're having a nice winter and enjoying the ability to go outside without sweating. On to our topic, let's ta

Jane:                                  Hi everyone, welcome to episode five of Getting Personal: A Mix of the Harsh. I'm Jane Ferguson an assistant professor at Vanderbilt University Medical Center and chair of the FGTB Professional Education and Publications Committee. This month we start off by discussing a topic that isn't strictly scientific but may have just as big of an impact on your career as your science, mentoring. I'll talk to Anna Pilbrow from the FGTB Early Career Committee on how you can find the right mentor for you. And if you've been around long enough that you know longer need any more mentoring, keep listening as we would love you to sign up to become a mentor and share your wisdom with the next generation. Then I'll talk to Naveen Pereira from Mayo Clinic, about some of the papers we've been reading this month.                                            So I'm here with Anna Pilbrow, who is a member of the FGTB Early Career Committee. So welcome Anna, and could you take a moment to intro

Jane Ferguson:                Hi, everyone. Welcome to Episode Four of Getting Personal: -Omics of the Heart." I'm Jane Ferguson, an assistant professor at Vanderbilt University Medical Center. This month, we have a special feature from early career member, Andrew Landstrom, who went to the Heart Rhythm Scientific Sessions in Chicago earlier this month and talked to some of the scientists who presented their research. So listen on for interviews Andrews conducted with Anneline te Riele, discussing the challenges and opportunities related to incidental findings in genetic testing, with Ernesto Fernandez, describing his research into whole exome sequencing and Long QT syndrome, and with David Tester, discussing novel variance and pathway analysis in Sudden Infant Death Syndrome. Andrew :                           My name is Andrew Landstrom and I am from the Baylor College of Medicine Department of Pediatrics' section on Cardiovascular Disease. I'm here at the 2017 Heart Rhythm Society Scientific Sessions. Anne

Jane:                   Hi. Welcome to episode three of Getting Personal, Omics of the Heart. I'm Jane Ferguson and this podcast is brought to you by The Functional Genomics and Translational Biology Council of The American Heart Association. In this episode, I talk to Jonathan Mosley about an interesting genetic method he has developed to look at shared genetic contributors that influence risk phenotypes, as well as disease risk, which can be used to integrate data from prospective studies with large scale electronic health record data. We also highlight a recent AHA scientific statement on genetic literacy and Nevine and I discuss the latest in precision medicine.                              Our large hurdle in implementing precision medicine will be to increase understanding of genetics and genomics amongst healthcare providers. Sima Mittal, Karen [inaudible 00:01:11] and colleagues tackled this issue as part of a recent AHA scientific statement published on behalf of The Council on Functional Genomics

Jane Ferguson:                Hello, and welcome to episode two of "Getting Personal: Omics of the Heart". I'm Jane Ferguson, an Assistant Professor of Medicine at Vanderbilt University Medical Center. This Podcast is brought to you by the Functional Genomics and Translational Biology Council of the American Heart Association.                                            If you're a current or prospective member of the American Heart Association but not yet affiliated with our council, I do encourage you to join us. FGTB is a vibrant council with a diverse membership spanning disciplines from basic research to clinical practice, with shared interests in genomics, precision medicine and translational research.                                            You can find out more by going to the AHA professional website at professional.heart.org and selecting FGTB from the list of scientific councils. If you're listening to this, you've obviously already figured out a way to access this Podcast. We do have several c

Jane Ferguson:                Hello, and welcome to episode one of Getting Personal: Omics of the Heart, a podcast from the Functional Genomics and Translational Biology Council of the American Heart Association. I'm Jane Ferguson, the current chair of the FGTB Professional Education and Publications Committee. This monthly podcast will bring you up to date with the latest in genomics, other omics technologies, and precision medicine as they relate to cardiovascular and metabolic disease.                                            In each episode, we'll give you an overview of some of the latest research to be published, and delve deeper into topics of particular interest. Whether you're a clinician, researcher, genetic counselor, or other healthcare or science professional, we hope these podcasts will be informative, and help you stay up to date with the latest developments in this exciting field.                                            In this episode, my colleague Naveen Pereira talks to Amit Khera ab