Authentic Biochemistry

Authentic Biochemistry

  • Autor: Vários
  • Narrador: Vários
  • Editora: Podcast
  • Duração: 434:45:48
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Sinopse

You have wisely landed upon Authentic Biochemistry, with Dr Daniel J Guerra, where published research and clinical science is interrogated.

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Episódios

  • BioiMedical Portrait III. NLRP3 Inflammasome and senescence-associated heterochromatic foci in macrophages, Kuppfer Cells and Liver sinusoidal endothelial cells contibute to liver/adipose disease

    BioiMedical Portrait III. NLRP3 Inflammasome and senescence-associated heterochromatic foci in macrophages, Kuppfer Cells and Liver sinusoidal endothelial cells contibute to liver/adipose disease
    30/09/2023 Duração: 29min

    References Telemann Georg P. 1765. Overture D Major, TWV 55:D18 | Tafelmusik https://youtu.be/8r-IFLtN9x4?si=T2hp65oGT--dTivY Leukemia 2020 volume 34, pages 75–86 Nat Cell Biol. 2019 Mar; 21(3): 397–407 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III.c12. Senescent cells from aging and obesity obtain chronic hyperinflammation of adipose associated leucocyte infiltrates potentiating alternating systemic proliferation or PCD.

    BioMedical Portrait III.c12. Senescent cells from aging and obesity obtain chronic hyperinflammation of adipose associated leucocyte infiltrates potentiating alternating systemic proliferation or PCD.
    28/09/2023 Duração: 29min

    References Haydn, Michael. 1760. Salve Regina in G MH32. https://youtu.be/u_Xjo5KJ3mg?si=kmKaaBJMvUgs_blX Leukemia 2020. volume 34, pages 75–86 CELL 2006. Volume 126, Issue 3, Pages 503-514 Nat Cell Biol. 2019 Mar; 21(3): 397–407. Curr Opin Pharmacol. 2021 Apr; 57: 107–116. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. AMPK regulation of ACC2 blocks MalCoA inhibition of CPTI allowing for fatty acid beta oxidation thus alleviating adipose obesity-induced macrophage pro-inflammation.DJGPhD.

    BioMedical Portrait III. AMPK regulation of ACC2 blocks MalCoA inhibition of CPTI allowing for fatty acid beta oxidation thus alleviating adipose obesity-induced macrophage pro-inflammation.DJGPhD.
    26/09/2023 Duração: 29min

    References Saint-Saens. C. 1886. Symphony 3 (avec orgue) OP.78 J Clin Invest. 2011 Dec 1; 121(12):4903–4915 Cell Metab. 2022 Dec 6; 34(12): 2036–2046.e8. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. c10. Ribosomal collision frequency is attenuated by ZAK and GCN2 via mutually exclusive signalling events, DJGPhD. 25.9.23. Authentic Biochemistry Podcast

    BioMedical Portrait III. c10. Ribosomal collision frequency is attenuated by ZAK and GCN2 via mutually exclusive signalling events, DJGPhD. 25.9.23. Authentic Biochemistry Podcast
    26/09/2023 Duração: 29min

    References Cell. 2020 Jul 23; 182(2):404–416.e14. Curr Genet. 2021 Feb; 67(1): 19–26. RNA Biol. 2023; 20(1): 737–749. published online 13sept23 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. c9. Amino acid deprivation-linked fall of polypeptide synthetic fidelity triggers downstream ribosomal stress response phenomena including kinase mediated cell fate sequalae.

    BioMedical Portrait III. c9. Amino acid deprivation-linked fall of polypeptide synthetic fidelity triggers downstream ribosomal stress response phenomena including kinase mediated cell fate sequalae.
    23/09/2023 Duração: 29min

    References Cell. 2020 Jul 23; 182(2):404–416.e14. Nature Communications 2020. volume 11,3146 Curr Genet. 2021 Feb; 67(1):19–26 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. c8. Unique mRNA upstream open reading frames direct both the integrated stress response and rare selective up-regulation of stress-correcting protein synthesis.DJGPhD.21.9.23

    BioMedical Portrait III. c8. Unique mRNA upstream open reading frames direct both the integrated stress response and rare selective up-regulation of stress-correcting protein synthesis.DJGPhD.21.9.23
    21/09/2023 Duração: 29min

    References Dr Guerra's lectures RNA Biol. 2023; 20(1): 737–749 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III.c.7 Elementary polypeptide synthesis-translation. Lecture 1. DJGPhD.20.9.23.Authentic Biochemistry Podcast.

    BioMedical Portrait III.c.7 Elementary polypeptide synthesis-translation. Lecture 1. DJGPhD.20.9.23.Authentic Biochemistry Podcast.
    20/09/2023 Duração: 30min

    Reference Dr Guerra's lecture notes --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. c6. Adipokine and the succinate receptor systems in obese adipose inflammation as regulated by AMPK.DJGPhD.19.9.23. Authentic Biochemistry Podcast

    BioMedical Portrait III. c6. Adipokine and the succinate receptor systems in obese adipose inflammation as regulated by AMPK.DJGPhD.19.9.23. Authentic Biochemistry Podcast
    20/09/2023 Duração: 29min

    References Cream 1968 Wheels of Fire J Neuroinflammation. 2019; 16: 34. Front Immunol. 2019; 10: 345. Cell Metabolism 2023. Volume 35 Issue 4. 601-619.e10 Sci Signal. 2017 Jan 31; 10(464):eaaf7478 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III.c.5. Adipokine mediated adipose inflamation is linked to the hypothalamic control over metabolism and systemic inflammation.DJGPhD.18.9.23.Authentic Biochemistry Podcast

    BioMedical Portrait III.c.5. Adipokine mediated adipose inflamation is linked to the hypothalamic control over metabolism and systemic inflammation.DJGPhD.18.9.23.Authentic Biochemistry Podcast
    18/09/2023 Duração: 29min

    References Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55 Int J Biol Sci. 2015; 11(11):1272–1280 Front. Physiol., 01 June 2018 Int. J. Mol. Sci. 2019, 20(6), 1505 Front Immunol. 2023; 14: 1149366 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. c.4. Adipose tissue macrophages express galectin binding proteins which alter immunosuppression and polarizationadipokines mediate the inflammatory response. DJGPhD.17.9.23

    BioMedical Portrait III. c.4. Adipose tissue macrophages express galectin binding proteins which alter immunosuppression and polarization;adipokines mediate the inflammatory response. DJGPhD.17.9.23
    17/09/2023 Duração: 29min

    References Luigi Boccherini: Symphony Op. 12 No. 4 in D Minor JCI Insight. 2016 Nov 17; 1(19): e87748 Front Immunol. 2023; 14: 1149366 Adv Biol Regul.2019 Jan;71:41-54. Int. J. Mol. Sci. 2019, 20(6), 1505 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. Immunometabolic disease 3c.Reactive N and O interconversions in obese adipose exacerbate systemic inflammation. 17.9.23. DJGPhD. Authentic Biochemistry Podcast.

    BioMedical Portrait III. Immunometabolic disease 3c.Reactive N and O interconversions in obese adipose exacerbate systemic inflammation. 17.9.23. DJGPhD. Authentic Biochemistry Podcast.
    17/09/2023 Duração: 29min

    References Inn Med (Heidelb). 2023 Apr;64(4):313-322. JBC 2001. Volume 276, Issue 31, August. Pages 28799-28805. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. Immunometabolic disease. The obesity-compromised adipose poise to hyperinflammation. DJGPhD. 15.9.23. Authentic Biochemistry.

    BioMedical Portrait III. Immunometabolic disease. The obesity-compromised adipose poise to hyperinflammation. DJGPhD. 15.9.23. Authentic Biochemistry.
    15/09/2023 Duração: 30min

    References Schubert, Franz. 1824. March.String Quartet #14 in D minor, D.810 Hypertension. 2002;39:1088–1094 Physiol Rev. 2018 Apr1;98(2):641-665. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait III. c1. Immuno-metabolic disease. Dr. Daniel J. Guerra. 14.9.23. Authentic Biochemistry Podcast.

    BioMedical Portrait III. c1. Immuno-metabolic disease. Dr. Daniel J. Guerra. 14.9.23. Authentic Biochemistry Podcast.
    15/09/2023 Duração: 30min

    References Schubert. F. 1826. "Ständchen" D.899 Immunol Rev. 2020 May; 295(1): 101–113. Nat Metab. 2022 Sep;4(9):1202-1213 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • Biochemical Energetics. Elementary Considerations chapter2. DJGPhD. 13.9.23 Authentic Biochemistry Podcast

    Biochemical Energetics. Elementary Considerations chapter2. DJGPhD. 13.9.23 Authentic Biochemistry Podcast
    13/09/2023 Duração: 29min

    References Biochemistry lectures: Guerra archives --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • Biochemical Energetics I Elementary Considerations. DJGPhD 12Sept23. Authentic Biochemistry Podcast.

    Biochemical Energetics I Elementary Considerations. DJGPhD 12Sept23. Authentic Biochemistry Podcast.
    12/09/2023 Duração: 30min

    References Biochem lecture notes --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait II. Hashimotos Thyroiditis prevalence in women linked to mitochondrial electron transport chain activity, ATP/ADP translocation, and potent autoantibodies to thyroid peroxidase.

    BioMedical Portrait II. Hashimoto's Thyroiditis prevalence in women linked to mitochondrial electron transport chain activity, ATP/ADP translocation, and potent autoantibodies to thyroid peroxidase.
    10/09/2023 Duração: 30min

    References Journal of Immunology Research Article ID 8263829 JAMA. 2021 Jun 15; 325(23): 2392–2393. Thyroid. 2014 Feb 1; 24(2): 371–382. Pol Arch Intern Med. 2022 Mar 30; 132(3): 16222. FEBS Letters.1997. (414): 258-262 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait II. c.14. Predominance of Hashimotos Thyroiditis in Women: is there a link to the decreased expression of TLR7 and the AMPK-alpha/Id3 axis on CD8+TE and Treg activity?

    BioMedical Portrait II. c.14. Predominance of Hashimoto's Thyroiditis in Women: is there a link to the decreased expression of TLR7 and the AMPK-alpha/Id3 axis on CD8+TE and Treg activity?
    10/09/2023 Duração: 29min

    References Mozart - Flute and Harp Concerto in C, K. 299 J Immunol Res. 2021; 2021: 8263829. J Immunol. 2022 Jan 1;208(1):155-168 Front. Immunol. 2022.31 March. Sec. Molecular Innate Immunity Volume 13 –202. Cells. 2022 Mar; 11(6): 997 Nature Immunology 2020. volume 21, pages1256–1266. Nature Immunology 2011. 12 (12) 10. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical PortraitII. c13. Female prevalent autoimmune RA-macrophage STAT3(TF) and NaMPT(NAD+ salvage pathway) promote rheumatoid arthritis amp primer on thyroiditis

    BioMedical PortraitII. c13. Female prevalent autoimmune RA-macrophage STAT3(TF) and NaMPT(NAD+ salvage pathway) promote rheumatoid arthritis & primer on thyroiditis
    09/09/2023 Duração: 30min

    References Cells. 2022 Mar; 11(6): 997. Nat Cell Biol. 2019 Mar; 21(3): 397–407. Rheumatology (Oxford). 2023 Jul; 62(7):2611–2620 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait II. C12. Lupus is far more common in women than men due to TLR7 enhancement and Rheumatoid Arthritis is more common in women due to macrophage bioeneregtic phenomenaDJGPhD.7Sept23

    BioMedical Portrait II. C12. Lupus is far more common in women than men due to TLR7 enhancement and Rheumatoid Arthritis is more common in women due to macrophage bioeneregtic phenomenaDJGPhD.7Sept23
    08/09/2023 Duração: 30min

    References Rheumatology (Oxford). 2023 Jul; 62(7):2611–2620 Science Immunology.2018.26 Jan Vol 3, Issue 1. Nature. 2020 Jun; 582(7813): 577–581. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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  • BioMedical Portrait II.c11. Autoimmune diseases like lupus are far more prevalent in women due to the lack of X chromosomal allelic inactivationof TLR7s. DJGPhD.7Sept23.Authentic Biochemistry.

    BioMedical Portrait II.c11. Autoimmune diseases like lupus are far more prevalent in women due to the lack of X chromosomal allelic inactivationof TLR7's. DJGPhD.7Sept23.Authentic Biochemistry.
    07/09/2023 Duração: 30min

    References Nature. 2020 Jun; 582(7813): 577–581 Science Immunology 2018.26 Jan Vol 3, Issue 1 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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