Authentic Biochemistry
- Autor: Vários
- Narrador: Vários
- Editora: Podcast
- Duração: 434:45:48
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Sinopse
You have wisely landed upon Authentic Biochemistry, with Dr Daniel J Guerra, where published research and clinical science is interrogated.
Episódios
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![ImmunoEpigenetics48. Importance of malic enzyme isoform subcellular distribution using 13CNMR -U13C C6 glucose isotopomer detection of pathway intermediates:GSIS vs. cancer.DJGPhD.21.3.23]()
ImmunoEpigenetics48. Importance of malic enzyme isoform subcellular distribution using 13CNMR -U13C C6 glucose isotopomer detection of pathway intermediates:GSIS vs. cancer.DJGPhD.21.3.23
21/03/2023 Duração: 30minReferences Methods Enzymol. 2009; 457: 425–450 Endocrinology, Volume 155, Issue 5, 1 May 2014, Pages 1653–1666 Am J Physiol Endocrinol Metab. 2008 Dec; 295(6): E1287–E1297 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
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![Immunoepigenetics 47. Intermediary metabolism re-enters the discussion on tumor corruption of cell division via diversion of glucose to NADPH production.DJGPhD]()
Immunoepigenetics 47. Intermediary metabolism re-enters the discussion on tumor corruption of cell division via diversion of glucose to NADPH production.DJGPhD
18/03/2023 Duração: 30minReferences Dr Guerra's lectures AJP Endocrinology and Metabolism. 2008. 295(6):E1287-97 Biochem Biophys Res Commun.1996 May 15;222(2):287-91 Carcinogenesis.2020 Jun; 41(4): 405–416 Oncogenesis 2017. volume 6, page e329. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
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![ImmunoEpigenetics 46.The Keap1/Nrf2/MAF axis in colorectal cancer: Methylation specific promoter mediated expression of anti-oxidant genes unveiling a complex role in tumorigenesis.DJGPhD.15.3.23]()
ImmunoEpigenetics 46.The Keap1/Nrf2/MAF axis in colorectal cancer: Methylation specific promoter mediated expression of anti-oxidant genes unveiling a complex role in tumorigenesis.DJGPhD.15.3.23
16/03/2023 Duração: 29minReferences Carcinogenesis. 2020 Jun; 41(4): 405–416 Rep Biochem Mol Biol. 2020 Apr; 9(1): 33–39 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics 45. Innate immune cell nSMASE generates ceramide mediated TLR signalling epigenetic alterations resulting in COX-2 electrophile PG- Michael adduct removal of KEAP/Nrf2 association.]()
ImmunoEpigenetics 45. Innate immune cell nSMASE generates ceramide mediated TLR signalling epigenetic alterations resulting in COX-2 electrophile PG- Michael adduct removal of KEAP/Nrf2 association.
12/03/2023 Duração: 29minReferences Carcinogenesis. 2020 Jun; 41(4): 405–416 Rep Biochem Mol Biol. 2020 Apr; 9(1): 33–39 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics 44. Ceramide and NRF2 mediate oxygen stress and the pro-inflammatory cytokine respose via association with chromatin epigenetic retailoring. DJGPhD.8March23. Authentic Biochemistry.]()
ImmunoEpigenetics 44. Ceramide and NRF2 mediate oxygen stress and the pro-inflammatory cytokine respose via association with chromatin epigenetic retailoring. DJGPhD.8March23. Authentic Biochemistry.
09/03/2023 Duração: 29minReferences Antioxidants (Basel). 2023 Feb; 12(2): 274 J Lipid Res. 2016 May; 57(5): 868–881. J Biol Chem. 2007 Jan 12;282(2):1384-96. J. Am. Chem. Soc. 2014, 136, 36, 12624–12630 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXXIII. In silico analysis of Rheumatoid Arthritis methylation patterns fails to obtain a general rule for epigenetic regulation of gene expression.DJGPhD07March23. ABPe]()
ImmunoEpigenetics XXXXIII. In silico analysis of Rheumatoid Arthritis methylation patterns fails to obtain a general rule for epigenetic regulation of gene expression.DJGPhD07March23. ABPe
08/03/2023 Duração: 30minReferences Int J Hematol 2022. 116, 828–836 Cancer Immunol Res (2022) 10 (1): 87–107 Front Immunol. 2022; 13: 881191 Nature Reviews Immunology 2018. volume 18, pages 617–634. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXXII. T-ALL Homeobox A gene alteration of MEF2C expressional variation linked to T-cell differentiation blockade as regulated by CaMK and HDAC4/HDAC5. DJGPhD. 05March23.]()
ImmunoEpigenetics XXXXII. T-ALL Homeobox A gene alteration of MEF2C expressional variation linked to T-cell differentiation blockade as regulated by CaMK and HDAC4/HDAC5. DJGPhD. 05March23.
06/03/2023 Duração: 28minReferences Biochem J 2012 444(1):105-114 Epigenetics. 2015 May; 10(5): 418–430. Nature Reviews Immunology volume 2018. 18, pages 617–634 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXXI. From Programmed Cell Death to Homeobox gene clusters, T-ALL leukaemias involve epigenetic events. DJGPhD.05March23. Authentic Biochemistry Podcast]()
ImmunoEpigenetics XXXXI. From Programmed Cell Death to Homeobox gene clusters, T-ALL leukaemias involve epigenetic events. DJGPhD.05March23. Authentic Biochemistry Podcast
05/03/2023 Duração: 29minReferences Genes & Diseases Available online 26 December 2022 Int J Mol Sci. 2021 May; 22(10): 5317 Haematologia 2016. Vol. 101 No. 6 June. Blood (2005) 106 (1): 274–286 Nature Reviews Immunology 2018. volume 18, pages 617–634. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXX. Transcription factor complex permutaions combine with histone acetylomic and methylomic covalent mofications in T -ALL disease. DJGPhD. 04 March 2023. Authentic Biochemistry.]()
ImmunoEpigenetics XXXX. Transcription factor complex permutaions combine with histone acetylomic and methylomic covalent mofications in T -ALL disease. DJGPhD. 04 March 2023. Authentic Biochemistry.
04/03/2023 Duração: 29minReferences Nature Reviews Immunology volume 18, pages 617–634 (2018) Genes (Basel). 2021 Aug; 12(8): 1118. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXIX. T cell acute lymphoblastic leukaemia genetics and epigenetics: the role of chromatin retailoring via histone LYS acetylation/deacetylation event ontology. DJGPhD.3March23]()
ImmunoEpigenetics XXXIX. T cell acute lymphoblastic leukaemia genetics and epigenetics: the role of chromatin retailoring via histone LYS acetylation/deacetylation event ontology. DJGPhD.3March23
04/03/2023 Duração: 29minReferences Genes (Basel). 2021 Aug; 12(8): 1118. Nature Reviews Immunology 2018. volume 18, pages 617–634. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXVIII. Tcell receptor activation and the PIP3/AKT/mTORCI/mTORCII control over cytokine expression:a primer. DJGPhD.2March2023.Authentic Biochemistry Podcast.]()
ImmunoEpigenetics XXXVIII. Tcell receptor activation and the PIP3/AKT/mTORCI/mTORCII control over cytokine expression:a primer. DJGPhD.2March2023.Authentic Biochemistry Podcast.
03/03/2023 Duração: 29minReferences Guerra's immunology lectures Experimental & Molecular Medicine volume 51, Article number: 80 (2019) Genes (Basel). 2021 Aug; 12(8): 1118 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXVII. Differential substrates for the Adenylate Cyclase-PKA phosphorylation cascade distributes assymetric inflammatory, hormonal and metabolic sequalae. DJGPhD.01March23.]()
ImmunoEpigenetics XXXVII. Differential substrates for the Adenylate Cyclase-PKA phosphorylation cascade distributes assymetric inflammatory, hormonal and metabolic sequalae. DJGPhD.01March23.
02/03/2023 Duração: 29minREferences Dr Guerra's graduate biochemistry lectures J Biol Chem. 2013 Mar 8; 288(10): 7137–7146 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigeneticsXXXVI. Tumor-specific methylation respondent transcription of Adenylate Cyclase 2 may be linked to differential cytokine expression controlling T cell activation. DJGPhD.01March23.]()
ImmunoEpigeneticsXXXVI. Tumor-specific methylation respondent transcription of Adenylate Cyclase 2 may be linked to differential cytokine expression controlling T cell activation. DJGPhD.01March23.
01/03/2023 Duração: 29minReferences Naunyn Schmiedebergs Arch Pharmacol . 2014 Apr;387(4):329-39. J Biol Chem. 2013 Mar 8; 288(10): 7137–7146 J Anim Sci. 1998 Jan;76(1):160-72 Journal of Bone Oncology 2017. Volume 9: 34-40 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![Immunoepigenetics XXXIV. Methylation signatures in neoplasias1. DJGPhD. Authentic Biochemistry Podcast Productions. 26.2.23]()
Immunoepigenetics XXXIV. Methylation signatures in neoplasias1. DJGPhD. Authentic Biochemistry Podcast Productions. 26.2.23
26/02/2023 Duração: 29minReferences Journal of Bone Oncology 2017. Volume 9, November. Pages 34-40 Journal of Disease and Global Health 15(3): 22-47, 2022.ISSN: 2454-1842, NLM ID: 101664146 https://www.ikppress.org/index.php/JODAGH/article/view/8023 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXIII. Crisper CAS , small molecule,and LOXP-CRE targeting of SDH/ComplexII decrease Th1 cytokine production: Standard Oxidation Potentials and TCA anapleurotic involvement.DJGPhD.]()
ImmunoEpigenetics XXXIII. Crisper CAS , small molecule,and LOXP-CRE targeting of SDH/ComplexII decrease Th1 cytokine production: Standard Oxidation Potentials and TCA anapleurotic involvement.DJGPhD.
24/02/2023 Duração: 29minReferences Nature. 2019 Jul; 571(7765): 403–407 Dr Guerra's lectures --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigeneticsXXXII. Apriori synthesis of the glycolytic/TCA/ETC axis mediating target and endogenous apoptotic control with Th and NK cell activation/proliferation and effector function. DJGPhD.]()
ImmunoEpigeneticsXXXII. Apriori synthesis of the glycolytic/TCA/ETC axis mediating target and endogenous apoptotic control with Th and NK cell activation/proliferation and effector function. DJGPhD.
22/02/2023 Duração: 29minReferences Authentic Biochemistry Podcast Immunoepigenetics lectures XXIX-XXX1 Dr. Guerra's intermediary metabolism and bioenergetics lectures Nature. 2019 Jul; 571(7765): 403–407 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXXI. The role of SDH on Complex II electron flow to ubiquinone subsequent to cardiac arrest is associated neuronal PCD similar to Tcell bioenergetic switching during activation.]()
ImmunoEpigenetics XXXI. The role of SDH on Complex II electron flow to ubiquinone subsequent to cardiac arrest is associated neuronal PCD similar to Tcell bioenergetic switching during activation.
19/02/2023 Duração: 30minReferences J of Intensive Care. 2020. volume 8, Article number: 60. Neuroscience. 2018 Nov 21;393:24-32 Cancers 2020, 12(11), 3237 Nature. 2019 Jul; 571(7765): 403–407 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![Immunoepigenetics XXX.NK lymphoyctes programed tumor cell death by titrating anti-apoptotic BCL proteins with BH3 pro-apoptotic events. DJGPhD. 17.2.23. Authentic Biochemistry Podcast]()
Immunoepigenetics XXX.NK lymphoyctes programed tumor cell death by titrating anti-apoptotic BCL proteins with BH3 pro-apoptotic events. DJGPhD. 17.2.23. Authentic Biochemistry Podcast
18/02/2023 Duração: 29minReferences Cancers (Basel). 2020 Aug; 12(8): 2137. Cell Death Dis. 2020 Jan 2;11(1):5 Cell. 2022. 185. 9. :521-1538.e18 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXIX. Apoptosis unthwarted:preventing phosphorylation of RNAPOLII tanks histone acetylation near Mcl enhancer region thus epigenetically inhibiting expression in glioblastoma cells.]()
ImmunoEpigenetics XXIX. Apoptosis unthwarted:preventing phosphorylation of RNAPOLII tanks histone acetylation near Mcl enhancer region thus epigenetically inhibiting expression in glioblastoma cells.
16/02/2023 Duração: 29minReferences Cell Death & Differentiation 2020.27: 3374–3385 Cell Death & Differentiation 2019. 26: 1501–1515 Cancers 2020, 12(8), 2137. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![A Dialectic on Research Scientific Method I. How research questions may be apprehended through the hypothetico-deductive-experimental paradigm. DJGPhD. 14.2.23]()
A Dialectic on Research Scientific Method I. How research questions may be apprehended through the hypothetico-deductive-experimental paradigm. DJGPhD. 14.2.23
14/02/2023 Duração: 29minReferences Guerra: lectures on research methods --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
