Authentic Biochemistry
- Autor: Vários
- Narrador: Vários
- Editora: Podcast
- Duração: 434:45:48
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Sinopse
You have wisely landed upon Authentic Biochemistry, with Dr Daniel J Guerra, where published research and clinical science is interrogated.
Episódios
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![ImmunoEpigenetics XXVIII, Synthesis of epigenetically controlled ferroptosis with Cyto-Toxic T Lymphocyte APC/MHC activated IFN-Gamma induced tumor fatty acyl CoA synthase- lipid peroxide mechanism.]()
ImmunoEpigenetics XXVIII, Synthesis of epigenetically controlled ferroptosis with Cyto-Toxic T Lymphocyte APC/MHC activated IFN-Gamma induced tumor fatty acyl CoA synthase- lipid peroxide mechanism.
14/02/2023 Duração: 29minReferences Cancer Cell 2020. 40, Issue 4, Pages 365-378.e6 Circulation Research. . 2004 May 28;94(10):1318-24. Mol Cell. 2020 Jun 18;78(6):1192-1206.e10 Cell. 2012 Aug 17;150(4):685-96 Cell Death Differ. 2020 May; 27(5): 1660–1676. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![Immunoepigenetics XXVII. PKM2 as an epigenetic and metabolic author of cell proliferation leading to tumorigenesis. DJGPhD. 12 Feb 2023. Authentic Biochemistry Podcast]()
Immunoepigenetics XXVII. PKM2 as an epigenetic and metabolic author of cell proliferation leading to tumorigenesis. DJGPhD. 12 Feb 2023. Authentic Biochemistry Podcast
13/02/2023 Duração: 30minReferences Mol Cell. 2014 Mar 6;53(5):700-9 Mol Cell. 2015 Sep 3;59(5):850-7 Cell & Bioscience 2019.Volume 9, Article number: 52. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXVI.The repressive deubiquitinase (PR-DUB) inhibits ubiquitinated histone 2A occupancy on SLC7A11 promoter causing cystine starvation and GSH depletion promoting ferroptosis. DJGPhD]()
ImmunoEpigenetics XXVI.The repressive deubiquitinase (PR-DUB) inhibits ubiquitinated histone 2A occupancy on SLC7A11 promoter causing cystine starvation and GSH depletion promoting ferroptosis. DJGPhD
11/02/2023 Duração: 29minReferences Cell Research. 2022. volume 32, pages 687–690 . --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![ImmunoEpigenetics XXV. Lymphocyte Specific Helicase inhibits ferroptosis while promoting tumorigenesis via fatty acid desaturase gene transcription and subsequent oleic acid formation via CoQ10.DJGPhD]()
ImmunoEpigenetics XXV. Lymphocyte Specific Helicase inhibits ferroptosis while promoting tumorigenesis via fatty acid desaturase gene transcription and subsequent oleic acid formation via CoQ10.DJGPhD
09/02/2023 Duração: 29minReferences Molecular Cancer 2020. volume 19, Article number: 39. Adv Exp Med Biol. 2021; 1301:41-57 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support
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![A Biochemical Partita 7th Movement. The articulation of obesity as arbiter of pathophysiology. DJGPhD. 04Feb23. Authentic Biochemistry.]()
A Biochemical Partita 7th Movement. The articulation of obesity as arbiter of pathophysiology. DJGPhD. 04Feb23. Authentic Biochemistry.
05/02/2023 Duração: 29minReferences and Inspiration Dr Guerra lecture notes https://youtu.be/uubKzLxxj1s --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![A Biochemical Partita 6th Movement. Human bioenergetics and hormonal regulation involving FA beta-oxidation and gluconeogenesis discourage glyoxylate cycle molecular evolution a priori. DJGPhD.]()
A Biochemical Partita 6th Movement. Human bioenergetics and hormonal regulation involving FA beta-oxidation and gluconeogenesis "discourage" glyoxylate cycle molecular evolution a priori. DJGPhD.
04/02/2023 Duração: 30minReferences and Inspirations Dr Guerra graduate biochemistry lectures https://youtu.be/156u4nV2uGE --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![A Biochemical Partita 5th Movement. The hepatic Malate Apartate Shuttle combined with the 2-oxoglutarate carrier facilitate reducing power and the OAA carbon source for cytosolic gluconeogenesis.]()
A Biochemical Partita 5th Movement. The hepatic Malate Apartate Shuttle combined with the 2-oxoglutarate carrier facilitate reducing power and the OAA carbon source for cytosolic gluconeogenesis.
04/02/2023 Duração: 29minReferences and Inspirations Dr Guerra's lecture notes-graduate biochemistry https://youtu.be/nP4nBxMtEug --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![A Biochemical Partita 4th Movement.Regulation of gluconeogenesis vs. glycolysis and the fatty acyl CoA beta-oxidation pathway provide REDOX and allosteric control over bioenergetics. DJGPhD.01FEB23.]()
A Biochemical Partita 4th Movement.Regulation of gluconeogenesis vs. glycolysis and the fatty acyl CoA beta-oxidation pathway provide REDOX and allosteric control over bioenergetics. DJGPhD.01FEB23.
02/02/2023 Duração: 29minReferences&Inspirations Guerra intermediary metabolic lectures https://youtu.be/nDidA8_gfbU --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![ImmunoepigeneticsXXIV. The Cathelicidin anitmicrobial peptide cysteine protease domain may contibute to innate immune defense against cancer via epigenetically regulated ferroptosis.DJGPhD.1Feb23]()
ImmunoepigeneticsXXIV. The Cathelicidin anitmicrobial peptide cysteine protease domain may contibute to innate immune defense against cancer via epigenetically regulated ferroptosis.DJGPhD.1Feb23
01/02/2023 Duração: 30minReferences Peptides . 2020 Jan;123:170177 Molecular Cancer. 2020. volume 19, Article number: 39. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![A Biochemical Partita 3rd movement. Principle of Sufficient Reason and the refutation of biological reductionism. DJGPhD.31.1.23. Authentic Biochemistry Podcast Productions]()
A Biochemical Partita 3rd movement. Principle of Sufficient Reason and the refutation of biological reductionism. DJGPhD.31.1.23. Authentic Biochemistry Podcast Productions
01/02/2023 Duração: 28minInspirations https://youtu.be/XkfsGCIiHb4 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![A Biochemical Partita. 2nd movement. DJGPhD. 29.1.23 Authentic Biochemistry Podcast Production]()
A Biochemical Partita. 2nd movement. DJGPhD. 29.1.23 Authentic Biochemistry Podcast Production
30/01/2023 Duração: 29minReferences Guerra lecture notes https://youtu.be/X0T6KysSejQ --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![A Biochemical Partita. Ist movement. DJGPhD. 28.1.23 Authentic Biochemistry Podcast Production]()
A Biochemical Partita. Ist movement. DJGPhD. 28.1.23 Authentic Biochemistry Podcast Production
28/01/2023 Duração: 29minInspiration https://music.youtube.com/watch?v=BR1_FhZdUIM&feature=share --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![ImmunoepigeneticsXXIII. Vitamin D hydroxylation mediated alteration of VDR chromatin retailoring and alteration of promoter methylation generate a dialectically ontological pathophysiology.DJGPhD.]()
ImmunoepigeneticsXXIII. Vitamin D hydroxylation mediated alteration of VDR chromatin retailoring and alteration of promoter methylation generate a dialectically ontological pathophysiology.DJGPhD.
28/01/2023 Duração: 29minReferences Sci Transl Med . 2015 Apr 8;7(282):282ra47 Cell Physiol Biochem . 2018;47(3):1060-1073 Hum Genomics. 2021; 15: 24 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Immunoepigenetics XXII. The role of circulating vitaminD in the regulation of innate immune antimicrobial peptide generation. DJGPhD. 25.1.23 Authentic Biochemistry]()
Immunoepigenetics XXII. The role of circulating vitaminD in the regulation of innate immune antimicrobial peptide generation. DJGPhD. 25.1.23 Authentic Biochemistry
26/01/2023 Duração: 30minReferences Hum Genomics. 2021; 15: 24 Nutrients. 2022 Jan; 14(2): 284 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![ImmunoepigeneticsXXI. Methylation patterns of CpG vs histone modification of specific loci must be sequenced to verify pathophysiological events. DJGPhD. 22.1.23 Authentic Biochemistry.]()
ImmunoepigeneticsXXI. Methylation patterns of CpG vs histone modification of specific loci must be sequenced to verify pathophysiological events. DJGPhD. 22.1.23 Authentic Biochemistry.
22/01/2023 Duração: 29minReferences Hum Genomics. 2021; 15: 24 JCI Insight. 2020 Sep 3;5(17):e138443 Nature Reviews Genetics volume 14, pages 204–220 (2013) --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![A Special Message for Authentic Biochemists. A direct way to contact your host and a little more. DJGPhD.21.1.23 Authentic Biochemistry Productions.]()
A Special Message for Authentic Biochemists. A direct way to contact your host and a little more. DJGPhD.21.1.23 Authentic Biochemistry Productions.
21/01/2023 Duração: 10minRather than referencing this episode I am enlisting your input. Please email me at our new email address: authenticbiochemistry@gmail.com Sincerely, Dr Guerra --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Immunoepigenetics XX. Inflammatory cytokines and associated transcription factors are controlled by epigenetically regulated microRNA. DJGPhD.20.1.23. Authentic Biochemistry.]()
Immunoepigenetics XX. Inflammatory cytokines and associated transcription factors are controlled by epigenetically regulated microRNA. DJGPhD.20.1.23. Authentic Biochemistry.
21/01/2023 Duração: 29minReferences Dr Guerra's micro RNA lectures FEBS J Volume278, Issue10 May 2011. Pages 1598-1609 International Journal of Molecular Sciences 2013. 14(11):22796-22816 Front. Genet., 07 September 2021 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![ImmunoEpigeneticsXIX. Diet-induced and db/db mouse model Type 2 diabetes is dissimilar to the human pathophysiology but shares epigenetic mechanisms controlling pro-inflammatory PLA2/COX2/PGE2.]()
ImmunoEpigeneticsXIX. Diet-induced and db/db mouse model Type 2 diabetes is dissimilar to the human pathophysiology but shares epigenetic mechanisms controlling pro-inflammatory PLA2/COX2/PGE2.
20/01/2023 Duração: 29minReferences Dr. Guerra's lipid lectures JCI Insight. 2020 Sep 3;5(17):e138443 Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7): 4061–4065. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![ImmunoepigeneticsXVIII. Variable DNA and histone methylation in cooperation with micro RNA mediate macrophage plasticity,inflammation and wound repair in T2D patients. DJGPhD.18.1.23.AuthenticBiochem.]()
ImmunoepigeneticsXVIII. Variable DNA and histone methylation in cooperation with micro RNA mediate macrophage plasticity,inflammation and wound repair in T2D patients. DJGPhD.18.1.23.AuthenticBiochem.
19/01/2023 Duração: 30minReference JCI Insight . 2020 Sep 3;5(17):e138443 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
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![Epistemological integration into realized metaphysicsV. Energy and mass like space and time are estimations of uncertain certainties yet are used as universals in physico-chemical event ontologies]()
Epistemological integration into realized metaphysicsV. Energy and mass like space and time are estimations of uncertain certainties yet are used as universals in physico-chemical event ontologies
16/01/2023 Duração: 30minReferences Thomas Hobbs-Leviathan Heraclitus-Collected Works --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
