Authentic Biochemistry

  • Autor: Vários
  • Narrador: Vários
  • Editora: Podcast
  • Duração: 434:45:48
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Sinopse

You have wisely landed upon Authentic Biochemistry, with Dr Daniel J Guerra, where published research and clinical science is interrogated.

Episódios

  • Biochemical Mosaic III. c.5. Gal3 and NRLP3 inflammasome coordinate inflammation via IL-1Beta convertase activation that is associated with NAFLD and NASH and inhibition of ABCA1 cholesterol efflux.

    25/03/2024 Duração: 29min

    References Infect Immun. 2013 Dec; 81(12): 4478–4489 Cell Cycle. 2022; 21(11): 1121–1139. The Journal of Nutritional Biochem.2023.Volume 112, 109217 Lightfoot, G. 1964. "Early Morning Rain" https://youtu.be/ZFJ5Bj_put0?si=m1Ue7rFfk_ggSLR3 Simon ,P. 1968. "Old Friends" SImon and Garfunkle Bookends LP. https://youtu.be/7A76lTte8qE?si=rfk3Q6wTA6Nsiok7 Mozart, WA. 1782 Serenade in C. Minor K.388. https://youtu.be/R6iSGBNdqSw?si=S2eGPmcySUhw4uvU --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical MosaicIII. C.4. My oppositional dialectic and episteme- metaphysical discourse on method+ Gal3 as proinflammatory lectin may not uniformly correlate with pathobiochemical events. DJGPhD.

    23/03/2024 Duração: 30min

    References Guerra, DJ. 2024. Uncollected writings. The Journal of Nutritional Biochemistry 2023. Volume 112, February. 109217 Walker, Cindy.1950 Blue Canadian Rockies. Cover "the Byrds"(1969). https://youtu.be/nzOHtU8Sb3c?si=5GAj7VPzIr7o0OO_t Heinichen J. D. 1711 (?)Concerto in A minor for violin https://youtu.be/V-E25Q-wjwc?si=bbWdZTNEUPGitY-S --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic III c.3. Bacterial glycosphingolipid mediated inflammasome activation and the Galectin:NLRP3 interaction pathophenocopy oxy-mtDNA TLR induction.DJGPhD.21.3.24

    22/03/2024 Duração: 28min

    References Front Immunol. 2020; 11: 591803 Am J Gastroenterol. 2004 Nov;99(11):2147-9. Biochem Biophys Res Commun. 2005 Dec 16;338(2):1031-6 Front Immunol. 2019 Jun 7;10:1309. FASEB J. 2021 May; 35(5): e21439. Hildegard von Bingen 1150.- "Canticles Of Ecstasy --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic III. C.2 A Non-canonical autophagic inhibition of NLRP3 inflammasome mediated inflammation in UVB-treated human keratinocytes.DJGPhD. 20.3.24.

    21/03/2024 Duração: 30min

    References Front Immunol. 2019 Jun 7;10:1309. JBC 2024 . March.Article in PressDOI:https://doi.org/10.1016/j.jbc.2024.107173 FASEB J. 2016 Dec;30(12):4202-4213. Nat Rev Gastroenterol Hepatol . 2020 Feb;17(2):93-110 Bach , JS. 1731. Piano Partita No. 2 In C Minor, BWV 826 https://youtu.be/f-OdOuNZciQ?si=AmFtC5CX3x2ndzdV Slade,Mann, and Rogers. 1975 "Time is Right" Manfred Mann https://youtu.be/jzJIej8h5q4?si=3-aCFe0tqur4lfX1 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic III. C.1. Inflammasomes. DJGPhD.19.3.24 Authentic Biochemistry Podcast

    20/03/2024 Duração: 30min

    References Immunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8 JBC 2024. March. Article in Press https://doi.org/10.1016/j.jbc.2024.107173 Schmelzer. J. H.1664 Sonatae unarum fidium. https://youtu.be/fB8G39y1uCA?si=ZMG2Zv9eKF3go0qR Hayward, J. 1967 "Tuesday Afternoon" Moody Blues https://youtu.be/fB8G39y1uCA?si=ZMG2Zv9eKF3go0qR Hayward, J. 1970 "Question" Moody Blues https://youtu.be/NP9iOqdxS8c?si=rfI3lzy0HhcffkWT --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical MosaicII.Book2.C.13.Dialectical event ontologies involving CNS plasmalogen and sphingolipid interlocution and the universality of Mozart and the Beatles. DJGPhD.17.3.24.Authentic Biochem.

    18/03/2024 Duração: 30min

    REferences Dr. Guerra. 2024.Previous Authentic Biochemistry Mosaic II lectures in the series Kant, I. 1790. Critique of Judgment. Mozart, WA. 1788. Sinfonie C-Dur KV 551 (»Jupiter«) https://youtu.be/6RbKWhr0o1c?si=xkt3QMG5aud__zLN Beatles. 1965. "Rubber Soul" https://youtu.be/kfSQkZuIx84?si=8QFvenLD4k8KLJD3 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II.Book 2. c.12 Adduced mTORC mediated glycerol-sphingolipid enzyme mRNA transcriptome association with Plasmalogen apodiction of myelination.DJGPhD.16.3.24

    17/03/2024 Duração: 29min

    References Developmental Cell 2022. Volume 57, Issue 6, 28 March Pages 691-706 Cell Rep. 2014 Feb 13; 6(3): 541–552. Dr Guerra: graduate lecture notes Mozart, WA 1791.Requiem in D Minor, K 626 https://youtu.be/YaH3zI0bYkM?si=X1yv50zY6nKTZmV9 Lennon/McCartney.1964 "I Don't Want to Spoil the Party" https://youtu.be/zqVDvLDLsjI?si=K1ve_5zJLZjqclsb --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • MosaicII,Bk.2.c.11 Squalene monooxygenase (SM) stabilization due to plasmalogen pathway fatty acid reductase deficiency promotes SM epoxidase alternate activity thus lowering24OHCHOL-LXR-myelination.

    14/03/2024 Duração: 29min

    References Dr Guerra-Graduate lipid biochemistry lectures Biochem J. 2022 Sep 30; 479(18): 1917–1940 Front Cell Dev Biol. 2022; 10: 946393. Nat Commun. 2019; 10: 97. Lennon-McCartney 1965. "Ive Just Seen a Face" https://youtu.be/m8LbJfC0SYM?si=gl_URu_yPTn9iZSd McShee, J./Traditional/Pentangle.1969 "Light Flight" https://youtu.be/2tyVezuUtCA?si=THxBJ0reUETkwDLa Mozart, WA. 1785.Piano Concerto No. 21 in C Major, K. 467 https://youtu.be/whTEVQ2OizI?si=YDMhOhlwmpKYqK-t --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II. Book2. c.10.Plasmalogen mediated oxy vs epoxy sterol synthesis may control cns inflammation and myelination given acid-catalyzed transacetalization sequalae.DJGPhD.12March24

    13/03/2024 Duração: 29min

    References Front Cell Dev Biol. 2022; 10: 946393. Adv Exp Med Biol. 2024:1440:149-161 Mozart, WA..1786.Horn Concerto in E-flat major # 4 KV 495 https://youtu.be/MMjqU461WpI?si=o2OWIijoe-mbF-pM Sebastian, J. 1968 She's a Lady https://youtu.be/xyFdzevDOHg?si=wgmv5z_jGrtA9x7c --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II. Book2. c.9. Plasmalogen regulation of composite ruling over prescriptive organization of cellular-biochemical phenomena includes florid mediation of the CNS.DJGPhD.11MARCH2024.

    12/03/2024 Duração: 29min

    References Journal of Cell Science 2019.Vol.132(6), 223016. Brain Research Bulletin 2023.Volume 194, March. Pages 118-123. Beethoven, LV. 1806. Violin Concerto D major, Op. 61 https://youtu.be/_hXdjRYELGw?si=0q5_qJCZu_zAZWoE Berry, C. 1956. "Roll Over Beethoven" ; as performed by the Beatles 1963 on LP "With the Beatles" https://youtu.be/Hz5jXwOXgKQ?si=FASk6PG2SAsEkrvP --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II.c.8 Cell death and CE-circ RNA vs.miRNA in Hepatocellular carcinoma: the spectre of AGPS et al. DJGPhD. 10March24.Authentic Biochemistry.

    11/03/2024 Duração: 29min

    References Cell Death Dis. 2020 Dec; 11(12): 1065. Genome Res. 2000 Oct; 10(10): 1445–1452. https://www.genecards.org/cgi-bin/carddisp.pl?gene=NIPBL Genes Dis. 2022 Jan; 9(1): 116–127 Schubert, F. 1824. Quartet 14 in D minor, D 810, "Death and the Maiden" https://youtu.be/XF_6vSlmm4w?si=CGTn3R6Tkn6LsMLv Browne,J. 1993. "Sky Blue and Black". https://youtu.be/Ty1I6dtC2zc?si=QHuwDiQUDh-4S5VP --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II.c.7. Fatty acid desaturation and mole% PC/PE/PL/CER are elevated via circRNA in Medublastoma while AGPS increased circRNA's in thyroid cancer.DJGPhD.7Mar24. Authentic Biochem.

    08/03/2024 Duração: 29min

    References Acta Neuropathologica Communications 2023. volume 11, Article number: 38 Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798 Front Mol Biosci. 2022; 9: 925389. Front Cell Dev Biol. 2021; 9: 636838 Oncol Lett 2018. 15: 7889-7899. Saint-Saëns, C. 1886. Symphony No 3 in C minor, Op 78 https://youtu.be/ZWCZq33BrOo?si=8hQ01E9jfp0eU07o Winwood,S. 1969. Had to Cry Today (Blind Faith) https://youtu.be/Z4Yo_VbGdMg?si=tWz0_qnG5Nsx5qxX --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II.c.6 Meduloblastoma is linked to plasmalogen and circ RNA phenomena that are pathophenocopied in other cancers. DJGPhD.5.Mar24.Authentic Biochemistry

    06/03/2024 Duração: 30min

    References Acta Neuropathologica Communications 2023. volume 11, Article number: 38 Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798. Int J Med Sci. 2022; 19(6): 975–985 Nature Communications 2022. volume 13, Article number: 1508 Lassus. O. 1578. Requiem - Missa pro defunctis (4vv) : Offertorium https://youtu.be/UXY4hxCvu7M?si=lcM_lw11lbPWrYX4 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II. c.5 Peroxisomal plasmalogen biosynthesis may regulate transcriptomic and proteomic sequalae to plasmamembrane mediated signal transduction. DJGPhD.4March24.

    04/03/2024 Duração: 30min

    References Front Physiol. 2021; 12: 730829. Non-coding RNA Investig 2017. 1:5. Genome Biology 2011. volume 12, Article number: 236 RNA Biol . 2021 Nov 12;18(sup2):574-585. Hunter. R. 1975. "Cruel White Water" https://youtu.be/T-oBD3F74Nk?si=zsrEBN0JKan_FXdH --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II. c.4. Peroxisomal biogenesis and AGPS-mediated plasmalogen synthesis involve circular RNA species that alter microRNA and mRNA expression in human cancers. DJGPhD.3MAR24.

    04/03/2024 Duração: 29min

    References Genome Res. 2004 Nov;14(11): 2245–2252. Int J Med Sci. 2022; 19(6): 975–985. Oncol Lett. 2018 May; 15(5): 7889–7899. Cell Death Dis. 2020 Dec; 11(12): 1065. RNA Biol . 2021 Nov 12;18(sup2):574-585 Bach, J Christian. 1775. Sinfonie Concertante https://youtu.be/S8NPgouJ5uk?si=_azSWNelNFRA2ai5 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Saturday Night Authentic Biochemistry The Agentic operator as metaphysical metaphor in metabolic regulation. DJGPhD.2March 2024.

    03/03/2024 Duração: 30min

    References Dr Guerra Archives: Graduate Biochemistry Lecture notes and syntheses Simon, P. 1969. The Boxer. https://youtu.be/l3LFML_pxlY?si=Nv5-mSzRu6fHP8Sr Boccherini, L. 1760. 7. Cellokonzert https://youtu.be/NSU6Ylxaobs?si=PZW0S3mWl25RwnE2 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II. c.3 Plasmalogen metabolism is coherently associated with peroxisomal integrity and replication. DJGPhD.01March 2024 Authentic Biochemistry.

    02/03/2024 Duração: 30min

    References Oncol Lett. 2018 May; 15(5): 7889–7899 Nat Genet. 1997 Apr;15(4):369-76 Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118609 Protein Cell 2018. 9, 196–206 Brain Research Bulletin 2023. 194: 118–123 The Moody Blues. 1968. "In Search of the Lost Chord" https://youtu.be/k5UdP-SFNgY?si=zDboUgA2LDi3E7m1 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II. C.2. Plasmalogen and PAF biosynthesis in relation to glycerol lipid and intermediary subcellular metabolism.DJGPhD.27.2.24

    28/02/2024 Duração: 29min

    References Guerra: graduate biochemistry lectures Chopin, F. 1830. Nocturne E Flat Major Op.9 No.2 https://youtu.be/tV5U8kVYS88?si=MKxfguVRI6hhQeMO Winwood, Wood and Capaldi 1967. Dear Mr Fantasy. Traffic. https://youtu.be/sS_eHdqcrM8?si=95X9RWJD2Q4w456S --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • Biochemical Mosaic II. Plasmalogens & other ether lipids. c.1 DJGPhD.26.2.24. Authentic Biochemistry Podcast

    26/02/2024 Duração: 29min

    References Cell Metab. 2014 Mar 4; 19(3): 380–392. Protein Cell 2018. 9, 196–206. Membranes 2023, 13(9), 764. Debussy , C. (. 1890;1905) Clair de lune. https://youtu.be/6zzWnxuQPWI?si=gcEAKpbgc9xO8esf Morricone. E. 1968. "Once Upon a Time in the West" https://youtu.be/j5eQ9UTmDLo?si=-eUjJ1s9hAd6fpwz Schubert, F. 1825. Ave Maria https://youtu.be/2H5rusicEnc?si=LcYisCODwtGgjjVx --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  • A Dialectical Interlocution with Mozart. DJGPhD.24.2.24 Authentic Biochemistry Podcast

    25/02/2024 Duração: 28min

    References Mozart.WA 1782. Fantasie in D minor. K.397 https://youtu.be/OYiz_u0tDwM?si=0dP736rTEkb4sauL 1785.Piano Concerto 22 in E flat Major.K.482 https://youtu.be/EJYPnrYNt8A?si=VqgS-PNw2bnbIFBj 1788.Divertimento in E♭ major, K. 563. https://youtu.be/2N4hHhTu4pw?si=p-VwHTTOK5ixFWfk 1787. Eine kleine Nachtmusik, K. 525. https://youtu.be/156u4nV2uGE?si=bRqysFpbi-6j0jMk --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

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