Authentic Biochemistry

Cell fate from Either ageing associated senescence to programmed cell death OR cell proliferation is finely tuned to the splice variant  expression of Cell Cycle dependent kinase inhibitors and the relative production of pro-inflammatory cytokines under the synchrony of DNA Damage Repair (DDR), telomerase expression decline, and the protective role of the Senescence Associated Secretory Phenotype (SASP). Dr. Daniel J. Guerra. 06 Dec 2021 Authentic Biochemistry Productions References: Oncotarget. 2013 Oct; 4(10): 1552–1553 Cancer Rep Rev. 2018 Mar; 2(2): 10 Nat Med. 2017 Jun; 23(6): 775–781 Cancer Genet Cytogenet. 1999 Mar;109(2):108-13. EBioMedicine 2016 830-39DOI: (10.1016/j.ebiom.2016.04.017 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message