Authentic Biochemistry

TLRs recognize molecular patterns associated with invasive pathogens. TIR domain-containing adaptors define the specificity of TLR signaling. TLR  interactions from CNS-resident microglia can obtain a pro-inflammatory environment that leads to neuronal degeneration as associated with classical aging related diseases like Parkinson's. J Neuroinflammation. 2014 Sep 20;11:166 Brain Behav Immun. 2019 Oct;81:41-51 J Mol Neurosci. 2021 Mar 9 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message