Authentic Biochemistry

•Cytokines regulate the intensity and duration of the immune response, and  they can act as growth factors or stimulants or even inhibitors of T cell amplification and differentiation. •Cytokines are glycoproteins that are synthesized through a dolichol PP mediated pathway in the ER and are thus dependent upon prenyl lipid metabolism Endoplasmic reticulum localized ADPGK serves glycoprotein synthesis and also functions to control glycolytic vs. aerobic bioenergetic intermediary metabolic agency in lymphocytes. Scientific Reports volume 9, Article number: 14248 (2019) --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message