Authentic Biochemistry
L-TRP is precursor to MEL and NAD ;Mel regulates Sirtuins which Perform DSB repair; NAD metabolism after SIRT activity yields PAR for SSB repair. DJGPhD 21 Oct 2020.
- Autor: Vários
- Narrador: Vários
- Editora: Podcast
- Duração: 0:28:54
- Mais informações
Informações:
Sinopse
The artificial enhancement of brain melatonin levels were hoped to suppress the progress of Alzheimer's Disease in humans and for correcting the circadian and sleep-wake disturbances associated with advanced aging.. However, given the complex association of melatonin on NAD+ tonicity and this relationship playing a role in DNA Damage Repair Responses (both SSB and DSB) . melatonin or a surrogate mimetic receptor agonist may have undesirable effects on neurodegeneration and oncogenesis in the CNS and the periphery. Dr Guerra opens this complex biochemical terrain in this and the previous 21 October Authentic Biochemistry podcast lectures. Please donate to AB! I need you ! • --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message