Dr Karin Love & Life

“Chemical Imbalance” Theory of Depression is Debunked. Plus, Where We’re Headed in Love & Life Ep. 200

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It’s our 200th episode—time to reflect on where we’ve been and where we’re headed! My first thought is how grateful I am for the opportunity to share with you and our community. Your comments, emails, and dms mean everything to me. They let me know you resonate with Love & Life’s mission:  “Conversations grounded in psych research to help us thrive in love and life.” On Love & Life, we’re all about the research–which is why we’re so dismayed by the degeneration of science we’ve recently witnessed. In this episode, we discuss 3 cases of faulty science which have just come to light, starting with an umbrella study by Joanna Moncrieff and colleagues which finds no connection between depression and serotonin levels. Although many psychiatrists have doubted the “chemical imbalance” explanation of depression for years, pharmaceutical companies continue to promulgate this unsubstantiated theory because it has, obviously, greatly boosted sales of antidepressants. We examine two other instances of manipul