The Doctor's Farmacy With Mark Hyman, M.d.

What Are Zombie Cells? | This episode is brought to you by Perfect Keto We used to think that aging is synonymous with decline but we’re now learning that this doesn’t necessarily have to be the case. We’re also learning that there are ways we can harness our body’s innate repair mechanisms to slow down, and even sometimes, reverse the aging process. One such way is to reduce the number of senescent--or zombie--cells that we have. So what are zombie cells, and how can we get rid of them? Dr. Hyman recently discussed this in his conversation with Dr. David Sinclair, Dave Asprey, and Max Lugavere. Dr. David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study longevity, aging, and how to slow its effects. More specifically, their focus is on studying sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as metabolism, neurodegener

The Keys To Aging Well | This episode is brought to you by Bioptimizers and Paleovalley When it comes to longevity, the goal isn’t just to live as long as possible. The true objective is to live as vibrantly and energetically as possible, for as long as possible. So how exactly do we do this? On this episode of The Doctor’s Farmacy, I was happy to sit down and talk with Dr. Frank Lipman about the biggest controlling factor when it comes to aging, the main longevity regulators in the body, and what we can do to activate them.  Dr. Frank Lipman is recognized as a vocal pioneer of integrative and Functional Medicine (or what he calls “good medicine”). Dr. Lipman is the founder of Eleven Eleven Wellness Center and the Chief Medical Officer at The Well. He is a sought-after international speaker and the best-selling author of six books—How to Be Well, The New Health Rules, Young & Slim for Life, Revive and Total Renewal—and his newest book, The New Rules of Aging Well: A Simple Program for Immune Resilience, Stren

How To Optimize Your Body’s Detoxification System | This episode is brought to by Thrive Market and my Dr. Hyman’s Sleep Master Course In a healthy body, the process of detoxification runs smoothly. But when we are toxic, the mechanism for detoxification in the liver gets sluggish, and certain toxins can remain active longer than we want or than our systems can handle. This makes us sick and impedes normal metabolism. It also causes fluid retention, bloat, puffiness, and more. In this episode, Dr. Hyman sits down with Maggie Ward to discuss the Functional Medicine approach to assessing your toxic load, and how certain foods, gut health optimization, and other lifestyle factors can enhance detoxification. Maggie Ward, MS, RD, LDN, is the Nutrition Director at The UltraWellness Center. Maggie holds a master’s degree in Nutrition from Bastyr University which focuses on using whole foods for holistic Nutrition Therapy. In addition, she completed her requirements to become a registered dietitian at Westchester Med

Why Food Should Be A Factor In Treating Mental Illness | This episode is brought to you by Find My Formula We know that our diet can have a major impact on mental health. Unfortunately, however, most medical education programs don’t include nutrition, so many psychiatrists and physicians, in general, aren’t as empowered as they should be to prescribe a healthy diet. Moreover, stigma around mental illness is still pervasive in our society and can keep people from feeling empowered that they can change their brain health and get the care they truly need. Dr. Hyman recently explored these topics with psychiatrists Dr. Daniel Amen and Dr. Drew Ramsey. Dr. Daniel Amen is the founder of Amen Clinics. Amen Clinics has the world’s largest database of brain scans related to behavior, totaling more than 160,000 SPECT scans on patients from 121 countries. Dr. Amen’s research team has published more than 70 scientific articles. He is the lead researcher on the world’s largest brain imaging and rehabilitation study on pro

Why Ice Water Immersion And Your Breath Is The Key To Health And Happiness | This episode is brought to you by ButcherBox and Four Sigmatic Frequent exposure to cold is linked to a number of different health benefits. Scientists have found evidence that exposure to cold speeds up metabolism, and reduces inflammation, swelling, and sore muscles. Many athletes use ice baths and other types of exposure to cold as a means to speed up recovery after physical exercise. Cold body therapy is also linked to improved quality of sleep, more focus, and even to an improved immune response. On this episode of The Doctor’s Farmacy, I was happy to sit down and talk with Wim Hof about the benefits of cold therapy and what happens to our body when we’re exposed to extreme cold conditions. Wim shares how we can change our biochemistry through our breathing, and the boundless capacities of the human spirit when we test our physical limits.  Wim Hof, also known as “The Iceman,” holds multiple world records for his feats of endura

Healing Psoriasis From The Inside Out with Dr. Todd LePine | This episode is sponsored by Bioptimizers and Farmacy Psoriasis is an autoimmune disease of the skin that predominantly involves scaling and inflammation. Aside from its physical manifestations, psoriasis can also result in debilitating psychological effects for those suffering with it. While conventional medicine typically treats psoriasis from the outside in, the reality is that it is an issue that comes from within, and should be treated from the inside out. Things like your genetics, diet, and environmental influences can all contribute to psoriasis.  In this episode, Dr. Hyman sits down with Dr. Todd LePine to discuss the Functional Medicine approach to treating psoriasis. They explain why addressing factors such as gut health, immunity, heavy metals, and more can all be instrumental in healing psoriasis. Dr. LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medici

How Gut Health Impacts Sleep | This episode is brought to you by Perfect Keto Getting quality sleep is one of the most important things we can do for our overall health and well-being. We know that things like getting outside first thing in the morning, going to sleep and waking at the same time each day, and putting away our devices one or two hours before bed can help ensure quality sleep. But did you know that the health of your gut microbiome also plays an important role in sleep quality? In this minisode, Dr. Hyman speaks with Shawn Stevenson about how the microbiome can affect sleep, and he also speaks with Dr. Elizabeth Boham about the Functional Medicine approach to optimizing gut health. Shawn Stevenson is the author of the international bestselling book Sleep Smarter and creator of The Model Health Show - featured as the #1 Health podcast on iTunes with millions of listener downloads each year. A graduate of The University of Missouri - St. Louis, Shawn studied business, biology, and kinesiology, an

How To Be A Food Activist In Your Own Kitchen | This episode is brought to you by Tushy, Perfect Keto, and Thrive Market We live in a world where our food is making us sick, tired, and overweight. Big Food brands design their packaged products to be addictive, so we over consume unhealthy ingredients, including cheap additives that are banned in other countries. Product labels are deceiving, hiding risky chemicals that contaminate our food and tout approval from organizations we’re led to believe are protecting our health, but in reality are doing anything but that.  On this episode of The Doctor’s Farmacy, I was so happy to talk to Vani Hari about how Big Food manipulates nutrition research, purposely makes their food addictive, and how we can regenerate our health by getting in the kitchen.  Named as one of the “Most Influential People on the Internet” by Time Magazine, Vani Hari is the revolutionary food activist behind foodbabe.com, co-founder of organic food brand Truvani, New York Times best selling aut

Why Muscle, Our Neglected Organ, Is The Key To Healthy Aging | This episode is brought to you by Paleovalley When it comes to longevity, the goal isn’t just to live as long as possible. The true objective is to live as vibrantly and energetically as possible, for as long as possible. So how exactly do we do this? On this episode of The Doctor’s Farmacy, I was happy to sit down and talk with Dr. Chris Rinsch and Dr. Stuart Phillips about the role of mitochondria in aging, and how we can use various compounds that are found in plants to upregulate our biology and increase not just our lifespan, but more importantly our healthspan. Dr. Chris Rinsch is the co-founder and CEO of Amazentis, an innovative life science company dedicated to employing breakthrough research and clinical science to bring advanced therapeutic nutrition products to life. Dr. Rinsch has authored original publications in leading scientific journals, including Nature Medicine, Gene Therapy and others, for his research on Urolithin A, mitochon

The Reemerging Field of Psychedelic Research | This episode is brought to you by Perfect Keto Hallucinogens like lysergic acid diethylamide (LSD) and psilocybin (a compound derived from certain species of mushrooms) were being researched in medicine as therapeutic agents before their recreational popularity boomed in the 1960s. Unfortunately, that era gave them a negative connotation and since then the research in medical psychedelics dramatically declined. Now, we are seeing a resurgence in interest for these types of therapies, and the research points to some positive benefits. One of the most astounding things about using various compounds, like psilocybin, as medicine is the long-lasting and powerful benefits of a single dose. Dr. Hyman sits down for a conversation with Dr. Anthony Bossis, where he shares about his experience conducting psychedelic research. Anthony P. Bossis, Ph.D. conducts FDA-approved clinical trials in the reemerging field of psychedelic research. He is a clinical psychologist and cli

How To Activate Nature’s Healing Potential | This episode is brought to you by Joovv and ButcherBox The microbiome has now come to be seen as the foundation for our overall health. The gut microbiome contributes to our digestive, immune, and emotional health, so it plays a vital role in overall well-being. Soil, like our gut, has its own microbiome, which supports the health of the plants growing in it. And just as our consumption of highly processed foods and overuse of antibiotics have destroyed key microbes in the human gut, we have also carelessly damaged the soil microbiome through overuse of chemical herbicides, pesticides, fertilizers and fungicides, heavy plowing and tillage, and the failure to add organic matter back into the soil. On this episode of The Doctor’s Farmacy, I was happy to sit down and talk with Dr. Zach Bush about why the health of our soil microbiome is the single most potent factor determining how healthy—or unhealthy—we are. We discuss why we need to acknowledge soil as a major infl

Cholesterol Is Not The Cause Of Heart Disease | This episode is brought  to you by Perfect Keto We have all heard that the secret to living a long, healthy, heart disease-free life is lowering your cholesterol, but is that really true? The reality is, most of us have little understanding about our cholesterol levels in our blood and the whole topic is much more complicated than we thought. Moreover, the standard cholesterol testing is outdated because it doesn’t check for particle size and particle number, and this information is what is needed to tell what’s really going on with your cholesterol.   In this episode, Dr. Hyman sits down with Dr. Elizabeth Boham to discuss why cholesterol is only one factor in determining your overall health. They also discuss the factors that influence your cholesterol and whether or not statin drugs are the most effective way to prevent heart attacks. Elizabeth Boham is a physician and nutritionist who practices functional medicine at The UltraWellness Center in Lenox, MA. Th

How To Pursue Your Dreams In Uncertain Times | This episode is brought to you by Four Sigmatic Taking action toward creating the life you want can be challenging, even in the best of times. It can seem even more daunting when present moment conditions are different than you’d expected them to be. And often, we can feel that we don’t have the time or space to focus on our own dreams.  Earlier this year, at the start of the coronavirus pandemic, Dr. Hyman spoke with Gabrielle Bernstein about the importance of taking spiritually aligned action toward the life you desire. Last year, he also explored how to create a vision for every area of your life with Jon and Missy Butcher. Gabrielle Bernstein is the #1 New York Times bestselling author of The Universe Has Your Back and has written six additional bestsellers, including Super Attractor which launched in September 2019. She was featured on Oprah’s Super Soul Sunday as a “next-generation thought leader” and The Oprah Winfrey Network chose Gabrielle to be part of

How Does Ultra-Processed Food Affect Our Mental Health? | This episode is brought to you by Thrive Market, Bioptimizers, and the Pegan Shake Currently, one in five Americans live with a mental illness, and these rates have been tracking alongside increases in metabolic disease. Yet, conventional psychiatric care does not typically include discussion of food or an assessment of metabolic dysfunction, obesity, or insulin resistance in the evaluation or treatment of mental health conditions. On this episode of The Doctor’s Farmacy, I was happy to sit down and talk with Dr. Shebani Sethi about the relationship between mental health and metabolic disease, and how we are gradually coming to understand that inflammation, oxidative stress, and insulin resistance may represent important root causes of many chronic brain illnesses, including many psychiatric disorders.  Dr. Shebani Sethi is a double board-certified physician in Obesity Medicine and Psychiatry. She is the Founding Director of Stanford University's Metab

Ask Mark Q&A #6: Natural vs. Artificial Sugars, Caffeine, Preparing For Pregnancy, And More | This episode is brought to you by Paleovalley and the Pegan Shake.  In this new Q&A series, Dr. Mark Hyman takes live questions from his community. For a chance to speak with Dr. Hyman during a future Ask Mark Q&A, text your question to 413-225-8995 using the hashtag #askmark Topics covered in this episode include: How our bodies process different types of sugars 5 Reasons High Fructose Corn Syrup Will Kill You Is caffeine good or bad for you? Preparing your body for pregnancy  Educating friends and family about healthy eating  This episode is brought to you by Paleovalley and the Pegan Shake.  Right now, Paleovalley is offering my listener's 15% off your entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. The Pegan Shake features a combination of collagen, pumpkin, and pea protein with healthy fats from my two favorites: MCT oil whic

Do Our Computers Know Us Better Than We Know Ourselves? | This episode is brought to you by Perfect Keto Studies have shown humans only actually remember 0.05% of our memories, whereas databases can remember it all! It’s a scary realization, but computers can know us in a way we don’t even know ourselves. We like to think we aren’t easily persuaded, but when companies know our likes, wants, needs, and purchase history it all adds up to an easier sale.  Earlier this year, Dr. Hyman sat down to discuss this topic with Andy Russell. Andy explains how big companies like Google and Facebook access and use our data. He also shares what we can do to maintain control over the content we see. Andy Russell is a digital media, ad-tech, marketing-tech, and data science innovator and pioneer as well as a self-taught Behavioral Economist. He has invested in, incubated, or run over 50 technology companies, including Daily Candy, Thrillist, Tasting Table, Idealbite, PureWow, Zynga, Betaworks, Business Insider, Sailthru, RapL

How Regenerative Agriculture Can Fix Our Health, Our Food System, And Our Planet | This episode is brought to you by ButcherBox and the Pegan Shake It can be easy to forget where our food really comes from. The overflowing shelves in the supermarket may trick you into thinking food just appears. The reality is that strong healthy soils are the foundation for food production, and without them, we can’t survive.  That’s why we need to shift our agricultural focus from growing commodity mono-crops like soy, corn, and wheat into a diversified system that encourages soil health, biodiversity, and sustainability for future generations. This is what regenerative agriculture is all about.  On this episode of The Doctor’s Farmacy, I was so happy to sit down and talk with Gabe Brown, one of the pioneers of the current soil health movement which focuses on the regeneration of our resources. Gabe and his family own and operate Brown's Ranch, a diversified 5,000-acre farm and ranch near Bismarck, North Dakota. The ranch c

Ask Mark Q&A #5: Celiac Disease, Mold Exposure, Gut Issues, And More | This episode is brought to you by the Pegan Shake In this new Q&A series, Dr. Mark Hyman takes live questions from his community. For a chance to speak with Dr. Hyman during a future Ask Mark Q&A, text your question to 413-225-8995 using the hashtag #askmark Topics covered in this episode include: Celiac disease Transitioning to a gluten-free diet Addressing mold exposure Testing for and treating physical mold toxicity  Healing in community Shared medical appointments Small intestinal bacterial overgrowth (SIBO) This episode is brought to you by the Pegan Shake. The Pegan Shake features a combination of collagen, pumpkin, and pea protein with healthy fats from my two favorites: MCT oil which is great for fat burning and brain power as well as avocado oil. I’ve also included acacia fiber to help with gut motility and digestion. Check it out at getfarmacy.com/peganshake. Mentioned in this episode: Dr. Hyman’s 10-Day Reset Dr. Hyman’s

How Does Your Body Make Energy? | This episode is brought to you by Perfect Keto If you think back to your early years of biology class, chances are you might recall learning about mitochondria, which are often equated to little energy factories. Mitochondria are the microscopic powerhouses hiding within most cells and they have huge consequences for our health. Damaged mitochondria can lead to a host of insults, including metabolic disease. Healthy mitochondria, on the other hand, can result in optimal aging. Dr. Hyman discussed the topic of mitochondria, and how we can best support them in recent conversations with Dave Asprey and Dr. Todd LePine.  Dave Asprey is the founder and CEO of Bulletproof 360, creator of the global phenomenon Bulletproof Coffee, a two-time New York Times bestselling author, the host of the Webby award-winning podcast Bulletproof Radio, serial entrepreneur, and global change agent. By employing the principles of biohacking (a term added to the Merriam-Webster Dictionary in September

How Feeding Hungry People Is An Act Of Love | This episode is brought to you by Tushy, Thrive Market, and the Pegan Shake Heroes run toward danger rather than away from it, and Chef José Andrés is no stranger to disaster zones. Over the past few years, he has responded to several major crises. After an earthquake devastated Haiti, Hurricane Maria ravaged Puerto Rico, wildfires scorched Southern California, and a refugee crisis intensified on the Venezuelan border, José quickly mobilized volunteer chefs to prepare meals for thousands of people in need through his non-profit, World Central Kitchen.  On this episode of The Doctor’s Farmacy, I was so happy to sit down and talk with José Andrés, an internationally-recognized culinary innovator, New York Times best-selling author, educator, humanitarian, chef, and owner of ThinkFoodGroup, the award-winning collective of nearly 30 restaurants throughout the country and beyond. A naturalized U.S. citizen originally from Spain, Andrés has been a tireless advocate for