Mds Podcast

What innovations in dystonia treatments do we have to look forward to? Dr. Mark Edwards sits down with Dr. Sarah Camargos to answer that vary question. 2023 Congress virtual access

Dr. Sarah Camargos interviews Dr. Thiago Leal and Dr. Ignacio Mata about the need of genetic studies on underrepresented populations and the technical challenges they faced when alayzing admixture ancestries and X chromosome. Read the article

In this special issue celebrating the Movement Disorders journal Research Article of the Year 2023, Sara Schaefer discusses with Dr. Mario Zappia the effects of the short vs long duration responses to levodopa on cortical excitability and neuroplasticity in response to motor learning tasks in early Parkinson’s disease patients. Read the article »

In this special issue celebrating the Movement Disorders Clinical Practice journal Research Article of the Year 2023, Sara Schaefer discusses tic phenomenology in primary tic disorders vs. functional tic-like disorders with Dr. Tamara Pringsheim. Read the article »

Dr. Wszolek shares with Dr. Schaefer his extensive knowledge about the clinical, genetic, and pathological findings in Perry disease, a rare and likely underdiagnosed parkinsonian condition. Read the article.

In this episode, Dr. Pierre-Emmanuel Sugier discusses the epidemiological associations between PD and cancers. While investigating several European GWAS databases, his group raised the conundrum whether cancer and Parkinson's disease share common risk factors. Read the article.

In this episode, we interviewed Prof. Jian Feng about his most recent paper covering the role of parkin mutations in human A9 dopaminergic neurons and role they play in locomotor activities of early-onset PD. Read the article.

In this episode, Michele Matarazzo highlights the relevance of our society for the field and its members, with special guest Njideka Okubadejo.

In this episode Dr. Tiago Outeiro talks with Dr. Andrew Siderowf about the exciting new results in his most recent publication on alpha-synuclein seed amplification assay. Read the article.

Dr. Michele Matarazzo interviews Dr. Talene Yacoubian on an article recently published on the Movement disorders journal that reveals increased inflammatory markers in recently diagnosed patients with Parkinson's disease without medication, suggesting the important role of inflammation from the early stages of the disease. Furthermore, inflammatory biomarkers are related to cognition. Journal CME is available until May 22, 2024 Read the article.

Dr. Christelle Nilles talks with Dr. Hugo Morales Briceno about the clinical presentations of Wilson’s disease patients with onset after 40 years and the challenges of diagnosing patients with atypical neurological manifestations. Read the article.

Sara Schaefer discusses the history, inner workings, and vision of the International Parkinson and Movement Disorder Society with current MDS President Francisco Cardoso.

Deep brain stimulation (DBS) has long been considered a risky procedure for people with Parkinson's disease and cognitive impairment. In this interview, Dr. Miocinovic presents real-world data, showing that DBS might be safe and useful in carefully selected patients with moderate cognitive impairment. Read the article.

In this History of Movement Disorders Special Episode, Prof. Tiago Outeiro interviews Prof. Maria Grazia Spillantini about integral work involved in discovering the role alpha-synuclein plays in the development of Lewy bodies. She discusses where the field is now and what questions young researchers should start asking.

In this special Hot Topics episode, Dr. Filip Scheperjans discusses what we know and what we don't yet know about the gut microbiome in Parkinson's disease, theories of influencing pathways within the gut-brain axis, and future directions for exploring and altering the gut microbiome in this patient population to impact disease.

Sara Schaefer discusses with Dr. Eduardo de Pablo-Fernandez his recent paper in Movement Disorders providing retrospective pathological validation of the 2022 MDS MSA Criteria using specimens from the Queens Square Brain Bank. Read the article.

In this paper, Dr. Vrustangkumar Shah and colleagues evaluated gait in patients with Parkinson's disease in the lab and in real life, with and without levodopa through wearable sensors. Some measures are able to discriminate fallers from non-fallers in PD. Read the article.

Two clinical trials with antibodies targeting alpha synuclein in early Parkinson's disease have been published in the New England Journal of Medicine. Anthony Lang and Gennaro Pagano, the first authors of the articles share the results and discuss the possible future perspectives with the MDS Podcast editor, Michele Matarazzo. Read the prasinezumab article. Read the cinpanemab article.

In part 5 of the Dystonia Special Series, Dr. Francesca Morgante interviews Dr. Jill Ostrem about current and future approaches to treatment of dystonia.

As part of the Dystonia Special Series, Dr. Francesca Morgante interviews Dr. Anna Sadnicka on the neural roots of dystonia.